Soh Lab

Mission Statement

Our laboratory is dedicated to developing biosensor systems for early disease detection and targeted therapies.  Toward this end, one arm of our laboratory develops novel molecular reagents (aptamers and engineered antibodies) that can perform molecular functions that conventional reagents cannot do – such as conformational switching and signaling.  We generate these novel reagents through rational design as well as the process of “directed evolution." The second arm of our laboratory develops advanced electronic and photonic hardware systems to integrate these reagents for deployment.  We are particularly interested in developing new technologies for measuring biomarkers in vivo – continuously, and developing novel diagnostic solutions that can be distributed - at scale - with minimal infrastructure.